Endocrine Abstracts

Introduction: Tertiary hyperparathyroidism can be developed in cases of persistent or non-curable secondary hyperparathyroidism or in any other case of long-standing hypocalcemia that leads to the autonomous function of at least one parathyroid gland. We present a case of a man with tertiary hyperparathyroidism and excessive maxilla swelling and extensive bone lesions.Presentation: A 32 years old man, with chronic renal failure on dialysis for twelve yea...

Introduction: Adrenal cystic lesions are rare. Differential diagnoses include pseudocysts, echinococcal cysts, hemangiomas, cystic pheochromocytomas, adrenal hematomas and lymphangiomas. We present here a rare case of an adrenal lymphangioma.Case report: A 35-year old man was referred to our department for investigation of a right adrenal cystic mass, incidentally found during an abdominal ultrasound. The patient was completely asymptomatic and had a med...

Introduction: IgG4 Related Hypophysitis (IgG4-RH) is a newly recognized form of hypophysitis. It usually appears as part of IgG4-Related Disease (IgG4-RD), an immune mediated disease, with manifestations in many organs. Isolated hypophysitis without other IgG4-RD manifestations is rare.Presentation: A 64 years old female referred to our department for further investigation of a 9 month history of fatigue, muscle weakness, recurrent episodes of right temp...

Introduction: Postmenopausal virilization with acute onset and rapid progression requires a thorough investigation for the presence of adrenal or ovarian tumor. We present here a challenging case of a radiologically not visible and rare androgen-hypersecreting ovarian tumor.Case report: A 71-year old postmenopausal woman presented to our department for the investigation of terminal hair growth, of recent onset and rapid progression, on the upper lip, chi...

Introduction: 17- α hydroxylase deficiency, an autosomal recessive disorder, is a rare cause of Congenital Adrenal Hyperplasia (CAH). The disease is usally diagnosed during infancy and childhood. We present here a rare case of an adult woman with 17-α hydroxylase deficiency diagnosed for first time in adulthood.Presentation: A 49 year old woman, with no previous medical history came to the emergency department of our hospital unconscious with G...

Introduction: Infectious diseases of the central nervous system (CNS) have been associated with hypopituitarism which relates to the severity, the localization and the cause of the infection. We present here a case of a CNS abscess and hormone deficiencies. A 53 years old man referred to the emergency department of our hospital with high fever and confusion and a 3 day history of weakness and anorexia. On clinical examination he was febrile (38.4oC), disoriented in ...

Introduction: Noonan syndrome is a genetic disorder that usually occurs on a sporadic basis (de novo mutuations) or with autosomal dominant inheritance. Patients present with dysmorphic facial features, cardiac disorders and short stature. Delay of puberty can also be noted. We present here an adult case of Noonan syndrome.Presentation: A 25 years old male presented to our department with low stature, decreased libido and absence of any secondary sexual ...

Introduction: Gonadal dysgenesis is a rare cause of primary amenorrhoea, and refers to a number of conditions in which gonadal development is abnormal leading to streak or hypoplastic gonads. We present a rare case of a girl with primary amenorrhea, tall stature, gonadal dysgenesis and karyotype 46,XX. A 15 years old girl with primary amenorrhoea referred to our department for futher investigation. On clinical examination she was tall (height 1.74 m), her weight was 76 kg and ...

Introduction: Empty sella syndrome (EES) is a condition often discovered incidentally, where the sella turcica, the structure containing the pituitary gland, appears to be empty. Patients either remain asymptomatic or, rarely, manifest signs of declined pituitary function. Patients experiencing hypopituitarism are offered hormonal replacement. Autopsy studies estimated a 5% EES prevalence among healthy individuals.Case report: A 68-year-old post-menopaus...

Introduction: Cushing’s syndrome is a rare (0.004%) hormonal disorder, which develops due to hypercortisolaemia. Cushing’s disease refers to a corticothroph cell pituitary tumour overproducing ACTH, which induces abnormally increased cortisol production from the adrenal glands. Cushing’s disease is a causative factor of osteoporosis, hypertension, glucose intolerance and dyslipidaemia.Case report: A 50-year old woman was referred to our de...